Mixing theory for culture and harvest in bioreactors of human mesenchymal stem cells on microcarriers
نویسندگان
چکیده
منابع مشابه
Serum-free media for mesenchymal stem cells expansion on microcarriers
Background Expansion of mesenchymal stromal cells (MSC) is one of the key steps for their use in tissue engineering or cell therapies. To increase cells expansion yields, two milestones have to be achieved that will allow a wider MSC therapeutic use, namely an optimal serum-free medium and a process intensification via 3D suspension culture on microcarriers [1]. Indeed, one of the major obstacl...
متن کاملIsolation, Culture, and Characterization of Human Dental Pulp Mesenchymal Stem Cells
Introduction Based on previous researches, dental pulp stem cells (DPSCs) are easily accessible with limited morbidity after collection. Their embryonic origin, from neural crests, explains their multipotency. DPSCs are primarily derived from the pulp tissues of the teeth.Objective: This study was undertaken to isolate, culture, and characterize two different third molar and first premolar hum...
متن کاملRevisiting the determination of hydromechanical stresses encountered by microcarriers in stem cell culture bioreactors
Background Expansion of mesenchymal stem cells (MSC) is one of the key steps for their use in tissue engineering or cell therapies. Today, expansion processes are mainly based on the use of microcarriers to allow large interfacial adherence areas [1]. However, this culture technology is known to be practically limited to low agitation intensity and microcarrier concentrations due to possible ce...
متن کاملHuman Mesenchymal Stem Cells and Their, Clinical Aapplication
There are two main categories for stem cells a cording to their origin: Embryonic Stem Cells and Adult Stem Cell. Mesenchymal stem cell, supporting hematopoetic stem cells in bone marrow, can regenerate tissues such as bone, cartilage, muscle, tendon and fatty tissue. These cells were recognized for the first time by Friedenstein and Petrokova who could isolate theme from rat bone marrow.Mesenc...
متن کاملTreatment with conditioned culture media with human mesenchymal stem cells on reserpine-induced thermal fibromyalgia model in rats
Background and Aims: Fibromyalgia (FM) is a chronic pain syndrome affected by the hippocampal function. Mesenchymal stem cells-conditioned medium (MSC-CMs) has shown antioxidant and neuroprotective potentials in treating various diseases. The present study aimed to investigate the efficacy of MSC-CMs on the thermal treatment of reserpine-induced FM and evaluate the concentration changes of tumo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Theoretical Foundations of Chemical Engineering
سال: 2016
ISSN: 0040-5795,1608-3431
DOI: 10.1134/s0040579516060117